Plasmodium falciparum clones and lines

 

A limited number of  standard parasite clones have been amplified and characterised, ready for use in standardised parasite assays, such as parasite growth inhibition (GIA), antibody-dependent cellular inhibition (ADCI) and as a source of parasite antigens, and for preparation of standardised slides for immunofluorescence assays. These include the 3D7, RO33, and Wellcome clones, which have been expanded to produce >50 vials of each tested clone. FCR3 and HB3 parasites have also been expanded by Dr. Ed Remarque, BPRC, Netherlands and should available from him on reqiest. 

All other lines and clones (>200 different lines/clones at present) are available but have not yet been formally tested for mycoplasma. As lines/clones are revived and characterised, we will add information on their mycoplasma status. 

Isolates and clones are from a diverse range of geographical locations, including

Brazil
Burundi
Cambodia
China
Colombia
Democratic Republic of Congo
Gambia
Ghana
Guinea
Honduras
Indonesia
Kenya
Liberia
Malaysia
Nigeria
Papua New Guinea
Senegal
Sierra Leone
Sri Lanka
Sudan
Tanzania
Thailand
Uganda
Vietnam
Zambia
Zimbabwe