3E12 (anti-Pfs 48/45)
Type:
Monoclonal antibody
Description:
Recognises the P. falciparum Pfs 48/45 antigen expressed on gametocytes of P. falciparum. Inhibitory in mosquito membrane feeding assays.
Subclone of:
Fusion 58
Isotype:
IgG1
Target:
Pfs 48/45
Fusion partner:
NS1
Source:
Prof. Richard Carter
History:
Hybridoma produced by immunisation of Balb/c mice with gametocytes of the 7G8 isolate of P. falciparum.
UK Biosafety level:
1
Availability:
Available. Enquire.
Please state in any acknowledgements, "Monoclonal antibody 3E12 (anti-Pfs 48/45) was obtained from The European Malaria Reagent Repository (http://www.malariaresearch.eu)". It is a condition of the supply of this reagent that you also cite the reference and source given above in any publication.