Plasmodium yoelii yoelii 17X (Pr1) clone

Type: 
Rodent malaria line
Description: 
P.y. yoelii 17X (Pr1) clone. Pyrimethamine-resistant subclone of 17X. After mosquito transmission.
Subclone of: 
isolate 17X
Country: 
Central African Republic
History: 
Isolated from naturally-infected Thicket Rats captured in CAR in 1965 (Landau and Chabaud). Passaged (Paris) and through mosquito (London). Uncloned isolate sent to Edinburgh from LSHTM, 1966. -> 10x mouse passage, 3x G. surdaster passage, 3x An. stephensi transmission, Pyrimethamine selection, 12x mouse passage, 28x G. surdaster passage, 15x An. stephensi transmission, cloning, 17X(Pr1) clone; deep froze stabilate 11/10/71.
UK Biosafety level: 
1
Availability: 
Enquire.
Please state in any acknowledgements, "Rodent malaria line Plasmodium yoelii yoelii 17X (Pr1) clone was obtained from The European Malaria Reagent Repository (http://www.malariaresearch.eu)". It is a condition of the supply of this reagent that you also cite the reference and source given above in any publication.